Psilocybin, which is produced by many species of mushrooms, is a naturally occurring psychedelic compounda group of substances that change or enhance sensory perceptions, thought processes, and energy levels which has shown substantial effects for managing anxiety and depression among people with cancer.
Psilocybin at a glance
Psilocybin is a naturally occurring psychedelic compound produced by many species of mushrooms, which are commonly called “magic mushrooms.” As a controlled substance in many countries, psilocybin can be obtained legally only in a few countries and some individual states or cities. It has one of the highest safety profiles among psychedelic substances, although medical supervision during use is advised.
Psilocybin has been studied for managing anxiety and depression among people with cancer, especially end-of-life anxiety. It shows substantial and lasting benefits from a single dose. Legal access currently is mainly through clinical trials, although Oregon has a system for legalized, supervised use.
CancerChoices ratings for psilocybin
We rate psilocybin on seven attributes, with 0 the lowest rating and 5 the highest. We rate the strength of the evidence supporting the use of psilocybin for a medical benefit, such as improving treatment outcomes or managing side effects.
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