Your Microbiome

Over thousands of years, our bodies have developed a symbiotic relationship with organisms living in and on our bodies, generally supporting each other’s health and well-being. Research links your microbiome—and changes in it—to several types of cancer and how well you respond to some conventional cancer treatments.

Your microbiome at a glance

Your microbiome is your personal collection of trillions of microorganisms that live on and within your body. It provides many essential functions, such as helping your digestion and supporting your immune system. Your microbiome influences your metabolism, your sleep cycles, and more. An out-of-balance microbiome can make your body terrainthe internal conditions of your body, including nutritional status, fitness, blood sugar balance, hormone balance, inflammation and more more supportive of cancer and can influence your response to some treatments.

Research links your microbiome—and changes in it—to several types of cancer, and especially colorectal and advanced lung cancer. The composition of your microbiome can also influence how well you respond to chemotherapy, immunotherapy, or stem cell transplant.

Some symptoms—such as gastrointestinal distress, itching, difficulty urinating, pain, rash, and more—might be telling you that your microbiome is out of balance. Your physician can order tests to diagnose an imbalance.

Antibiotics and some cancer treatments, such as chemotherapy or radiotherapy, can disrupt your microbiome. Surgery involving your digestive organs can also disrupt your microbiome. Taking probiotics with your surgical team’s supervision both before and after surgery may return your microbiome to balance quickly. What you eat is also key to creating and maintaining a healthy microbiome.

Top practices and therapies for managing your microbiome

Therapies we have reviewed


Laura Pole, MSN, RN, OCNS

Senior Clinical Consultant
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Laura Pole is senior clinical consultant for CancerChoices. Laura is an oncology clinical nurse specialist who has been providing integrative oncology clinical care, navigation, consultation, and education services for over 40 years. She is the co-creator and co-coordinator of the Integrative Oncology Navigation Training at Smith Center for Healing and the Arts in Washington, DC. Laura also manages the “Media Watch Cancer News That You Can Use” listserv for Smith Center/Commonweal. In her role as a palliative care educator and consultant, Laura has served as statewide Respecting Choices Faculty for the Virginia POST (Physician Orders for Scope of Treatment) Collaborative as well as provided statewide professional education on palliative and end-of-life care for the Virginia Association for Hospices and Palliative Care.

For CancerChoices, Laura curates content and research, networks with clinical and organizational partners, brings awareness and education of integrative oncology at professional and patient conferences and programs, and translates research into information relevant to the patient experience as well as clinical practice.

Laura sees her work with CancerChoices as a perfect alignment of all her passions, knowledge and skills in integrative oncology care. She is honored to serve you.

Laura Pole, MSN, RN, OCNS Senior Clinical Consultant

Nancy Hepp, MS

Lead Researcher
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Ms. Hepp is a researcher and communicator who has been writing and editing educational content on varied health topics for more than 20 years. She serves as lead researcher and writer for CancerChoices and also served as the first program manager. Her graduate work in research and cognitive psychology, her master’s degree in instructional design, and her certificate in web design have all guided her in writing and presenting information for a wide variety of audiences and uses. Nancy’s service as faculty development coordinator in the Department of Family Medicine at Wright State University also provided experience in medical research, plus insights into medical education and medical care from the professional’s perspective.

Nancy Hepp, MS Lead Researcher

Andrew Jackson, ND

Research Associate
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Andrew Jackson, ND, serves as a CancerChoices research associate. As a naturopathic physician practicing in Kirkland, Washington, he teaches critical evaluation of the medical literture at Bastyr University in Kenmore, Washington. His great appreciation of scientific inquiry and the scientific process has led him to view research with a critical eye.

Andrew Jackson, ND Research Associate

Last update: April 21, 2024

Last full literature review: July 2021

CancerChoices provides information about integrativein cancer care, a patient-centered approach combining the best of conventional care, self care, and evidence-informed complementary care in an integrated plan cancer care. We review complementaryin cancer care, complementary care involves the use of therapies intended to enhance or add to standard conventional treatments; examples include supplements, mind-body approaches such as yoga or psychosocialtherapy, and acupuncture therapies and self carelifestyle actions and behaviors that may impact cancer outcomes; examples include eating health-promoting foods, limiting alcohol, increasing physical activity, and managing stress practices to help patients and professionals explore and integrate the best combination of conventionalthe cancer care offered by conventionally trained physicians and most hospitals; examples are chemotherapy, surgery, and radiotherapy and complementary therapies and practices for each person.

Our staff have no financial conflicts of interest to declare. We receive no funds from any manufacturers or retailers gaining financial profit by promoting or discouraging therapies mentioned on this site.

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