Diindolylmethane (DIM) is created naturally when you digest cruciferous vegetables, and it’s also a nutritional supplement with possible anticancer effects.
How do experts use diindolylmethane?
Integrative experts provide recommendations for DIM in treating people with cancer. Learn more about the approaches and meanings of recommendations: Integrative Oncology Programs and Expert Guidelines ›
Published protocols, programs, and approaches
These protocolsa package of therapies combining and preferably integrating various therapies and practices into a cohesive design for care, programs, and approaches by leaders in integrative cancer care use or recommend this therapy or practice.
We do not recommend specific integrative protocols or programs but provide information for you to evaluate with your healthcare team.
Lise Alschuler, ND, FABNO, and Karolyn Gazella
Alschuler LN, Gazella KA. The Definitive Guide to Cancer, 3rd Edition: An Integrative Approach to Prevention, Treatment, and Healing. Berkeley, California: Celestial Arts. 2010.
Alschuler LN, Gazella KA. The Definitive Guide to Thriving after Cancer: A Five-Step Integrative Plan to Reduce the Risk of Recurrence and Build Lifelong Health. Berkeley, California: Ten Speed Press. 2013.
This book describes approaches for certain cancer types, or along with certain conventional therapy treatments, or for particular conditions such as insulin resistance.
Uses of diindolylmethane:
- Breast cancer
- Colon cancer
- Endometrial cancer
- Lung cancer
- Prostate cancer
Keith Block, MD
Block KI. Life over Cancer: The Block Center Program for Integrative Cancer Care. New York: Bantam Dell. 2009.
The integrative Block Program has recommendations to people who are at different places along the cancer continuum:
- Those who’ve been recently diagnosed
- Those in treatment
- Those who’ve concluded treatment and need to remain vigilant to prevent recurrence
Gerald M. Lemole, MD; Pallav K. Mehta, MD; and Dwight L. McKee, MD
Lemole GM, Mehta PK, McKee DL. After Cancer Care: The Definitive Self-Care Guide to Getting and Staying Well for Patients with Cancer. New York, New York: Rodale, Inc. 2015.
These doctors present easy-to-incorporate lifestyle changes to help you “turn on” hundreds of genes that fight cancer, and “turn off” the ones that encourage cancer, while recommending lifestyle approaches to address each type.
Uses of diindolylmethane:
- Bladder cancer
- Breast cancer
- Colon cancer
- Leukemia
- Lymphoma
- Prostate cancer
- Thyroid cancer
Neil McKinney, BSc, ND
McKinney N. Naturopathic Oncology, Fourth Edition. Victoria, BC, Canada: Liaison Press. 2020.
This book includes descriptions and uses of many natural and complementary protocols for cancer in general and for specific cancers. It also includes information on integrative support during conventional cancer treatment.
Uses of diindolylmethane:
- General cancer
- Breast cancer
- Cervical cancer
- Colorectal cancer
- Head and neck cancer
- Kidney cancer
- Leukemia
- Lymphoma
- Multiple myeloma
- Ovarian cancer
- Pancreatic cancer
- Prostate cancer
- Uterine cancer
Gurdev Parmar, ND, FABNO, and Tina Kaczor, ND, FABNO
Parmar G, Kaczor T. Textbook of Naturopathic Oncology: A Desktop Guide of Integrative Cancer Care. 1st edition. Medicatrix Holdings Ltd. 2020.
This book provides information on the treatment of 24 cancers, plus the most effective treatments of the most common symptoms affecting cancer patients while they undergo chemotherapy, radiotherapy, or surgery.
Uses of diindolylmethane:
- Breast cancer
Dosing
No optimal DIM dose in cancer prevention or treatment has been established.
Dosage recommendations are available from NatMed ›
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General information about dosing
Find general dosing guidelines regarding natural products and supplements in Dosing Guidelines ›