Managing your stress response

Top practices and therapies for managing your stress

Therapies and practices we have reviewed—the effects of these practices and therapies are described below.

Further therapies reported to help manage stress are listed below.

Symptoms of stress

Stress can show up as distressemotional, social, spiritual, or physical pain or suffering that may cause a person to feel sad, afraid, depressed, anxious, or lonely; people in distress may also feel that they are not able to manage or cope with changes caused by normal life activities or by having a disease, such as cancer or other symptoms.

If you experience anxiety, depression, sleep disruption or other symptoms, and you think stress may be contributing to them, you may need to address both your symptoms and the underlying stress to find relief and wellness.

One possible way that stress can be expressed is through anger. Both people with cancer and those caring for them can become angry, with the potential for abuse or even violence.1Mejri N, Lajnef I et al. Intimate partner violence after cancer diagnosis: an SOS call. Supportive Care in Cancer. 2023 Jan 9;31(2):103. We encourage you to reach out for help if you find yourself or your partner is becoming angry and not managing your anger response well.

Find information about assessing and communicating distress to your health care team including tools to help measure your distress.

Stress inventory: creating a stress score

The Holmes-Rahe Stress Inventory assigns a score to the top stressors in people’s lives to assess their risk of developing a stress-induced breakdown.2American Institute of Stress. The Holmes-Rahe Stress Inventory. Viewed March 7. 2022. If you use this inventory and find that you have a high risk, we encourage you to take your result and your concerns to your oncology team to work with you on managing your stress responses.

Post-traumatic stress disorder or other serious conditions

Post-traumatic stress disorder (PTSD) frequently develops after traumatic experiences. If you, either as a person with cancer or a caregiver, have a risk factor for PTSD, or you have symptoms of PTSD or any other symptoms of serious mental health issue, we encourage you to notify your cancer care team as soon as possible. Symptoms include these:3Mayo Clinic Staff. Post-traumatic stress disorder (PTSD). Mayo Clinic. Viewed March 7, 2022.

  • Intrusive memories
  • Avoidance
  • Negative changes in thinking and mood
  • Changes in physical and emotional reactions
  • Suicidal thoughts

What practices and therapies can help with stress?

Both self-care practices and some complementary therapies can help you manage your stress response.

Stress can be both mental/emotional and physical. We assess the evidence for various practices and therapies related to stress among people with cancer. We provide summaries here, but full details are on the therapy review pages.

As research evidence is often incomplete, learning how integrative experts manage stress can be informative. See How do integrative experts manage stress ›

Therapies and practices which are beneficial in some situations may show no benefit in others.

In this video from The Juniper Center, Lindsay McDonell, author of Your Dance with Cancer, discusses her approach for managing fear and stress and opening space in her life for joy.

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Practices and therapies with good or modest evidence of benefit for managing stress

Good evidencesignificant effects in one large or several mid-sized and well-designed clinical studies (randomized controlled trials (RCTs) with an appropriate placebo or other strong comparison control or observational studies that control for confounds) (this is the CancerChoices definition; other researchers and studies may define this differently) indicates that the practice or therapy is linked to the outcomes described with reasonable certainty. Modest evidencesignificant effects in at least three small but well-designed randomized controlled trials (RCTs), or one or more well-designed, mid-sized clinical studies of reasonably good quality (RCTs or observational studies), or several small studies aggregated into a meta-analysis (this is the CancerChoices definition; other researchers and studies may define this differently) means the practice or therapy may be linked to the outcomes described, but with a lower degree of certainty.

The evidence for these effects is described in the reviews available through the image links.

Moving More: modest and preliminary evidence

Lower physical markers of stress among people participating in exercise or movement (modest evidence)

Less perceived stress during active surveillance among people with prostate cancer participating in high-intensity interval training (preliminary evidence)

Creating a Healing Environment: modest evidence

Not specific to cancer:

  • Faster stress-recovery processes in laboratory experiments and better self-reported health conditions among people listening to positive soundscapes (modest evidence)
Sharing Love and Support: good and modest evidence

Loneliness and isolation are stressorschallenging situations. Feeling supported and loved can help you manage these stressors and others.

Not specific to cancer:

  • Less distress among people with higher levels of social support (good evidence)
  • Fewer symptoms of posttraumatic stress and more posttraumatic growth among adults with cancer with higher levels of social support (modest evidence)
Guided imagery: mixed evidence

Guided imagery is often used with relaxation techniques. Different effects are found in different circumstances.

Less stress or tension during radiotherapy among people treated with relaxation training and imagery (modest evidence)

Less distress among people recently diagnosed with cancer participating in progressive muscle relaxation with guided imagery (preliminary evidence)

Less stress after cancer treatment among people treated with imagery (preliminary evidence)

Less tension among parents of hospitalized children with cancer participating in progressive muscle relaxation and guided imagery (preliminary evidence)

No evidence of an effect on distress among people with cancer and with pain participating in relaxation and visualization training in a preliminary study

Not specific to cancer

  • Better levels of stress hormones after surgery among people treated with guided imagery and relaxation (preliminary evidence)
Probiotics and prebiotics: mixed evidence

Not specific to cancer:

  • No evidence of an effect on stress among people with symptoms of stress treated with probiotics in a combined analysis of studies (not specific to cancer)
  • Less perceived stress among healthy volunteers treated with probiotics (not specific to cancer) (modest evidence)
  • A lower marker of stress 5 to 7 days after elective orthopedic or colorectal surgery among elderly people treated with probiotics (not specific to cancer) (preliminary evidence)
Support groups and interventions: modest and preliminary evidence

In-person group: Less stress or distress among women with breast cancer participating in an in-person group (modest evidence)

Online groups: Insufficient (conflicting) evidence of an effect on stress or distress among women with breast cancer participating in an online support intervention

One-on-one peer support: Insufficient (conflicting) evidence of less distress among women with cancer or at risk of cancer receiving one-on-one peer support

Supportive community-based workbook-journal: fewer symptoms of stress among women with breast cancer receiving a supportive community-based workbook-journal (preliminary evidence)

Tai chi or qigong: good evidence

Lower markers of stress among people with cancer practicing tai chi or qigong (good evidence)

Time in nature or forest bathing: modest evidence

Not specific to cancer:

  • Lower risk of stress-related disorders among people with dense vegetation near their residences (modest evidence)
  • Less stress and annoyance among people listening to nature-based sounds (modest evidence)
Yoga: good to weak evidence

Less psychological stress or distress among people with cancer practicing yoga (good evidence)

Less stress before chemotherapy among people with cancer participating in laughter yoga (preliminary evidence)

Less psychological distress among caregivers for people with cancer practicing Vinyasa yoga (weak evidence)

Therapies with preliminary or weak evidence of benefit

Preliminary evidencesignificant effects in small or poorly designed clinical studies OR conflicting results in adequate studies but a preponderance of evidence of an effect (this is the CancerChoices definition; other researchers and studies may define this differently) means the practice or therapy may be linked to the outcomes described, although substantial uncertainty remains. Weak evidenceone or more case studies, supported by animal evidence OR small treatment effects of limited clinical significance OR studies with no controls OR weak trends of effects (this is the CancerChoices definition; other researchers and studies may define this differently) may mean that the effects are small or that a high degree of uncertainty remains about the links between the practice or therapy and the outcomes described.

Eating Well Learn moreSee Less
Acupuncture Learn moreSee Less
Healing touch Learn moreSee Less
Polarity therapy Learn moreSee Less
Relaxation techniques Learn moreSee Less
Enhanced recovery after surgery Learn moreSee Less

No evidence of an effect on managing stress

Moderate body weight loss ›

Distress is linked to increased body mass index (BMI) and greater waist circumference. However, a combined analysis of studies found no evidence of an effect of moderate weight loss (about 8 pounds) on self-reported stress among overweight or obese adults. We don’t know if more or less weight loss than that has an effect.

Stimulants such as ephedra, ginseng, and bitter orange can increase your stress response.

Further therapies

Further therapies used to manage stress that we haven’t reviewed for effectiveness or safety.

  • 5-HTP 
  • Alpha-lipoic acid
  • Ashwagandha 
  • Breathing therapies
  • Chamomile 
  • Cranial electrotherapy stimulation
  • Eye movement desensitization and reprocessing
  • Hops
  • Hypnotherapy
  • L-theanine
  • L-tyrosine 
  • Lavender
  • Lemon balm
  • Lobelia (Indian tobacco)
  • Magnesium
  • Magnolia bark and phellodendron
  • Meditation
  • Mimosa tree bark
  • Music therapy
  • Panax ginseng (Asian ginseng) 
  • Passionflower
  • Phosphatidylserine
  • Rhodiola rosea 
  • Schisandra
  • Siberian ginseng (Eleutherococcus senticosus
  • Valerian
  • Vervain (verbena)
  • Vitamin B₁ (thiamine) 
  • Vitamin B₅ (pantothenic acid) 
  • Vitamin C ›

Recommendations especially for caregivers with stress

These practices and approaches are recommended specifically for caregivers.4Mayo Clinic staff. Caregiver stress: Tips for taking care of yourself. Mayo Clinic. March 22, 2022. Viewed May 24, 2022.

  • Accept help
  • Focus on what you are able to provide
  • Set realistic goals
  • Get connected
  • Join a support group
  • Seek social support
  • Set personal health goals
  • See your doctor if you’re having trouble sleeping

In this Wellness Wednesday episode, Missy Hall conducts a sound bath meditation to calm the nervous system

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Helpful links

From the American Society of Clinical Oncology

Managing Stress ›

Free mobile app, but full functionality requires purchase of a sensor to provide heart rate variability coherence feedback

Relieving Stress and Anxiety ›

Keep reading


Laura Pole, RN, MSN, OCNS

Senior Clinical Consultant
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Laura Pole is senior clinical consultant for CancerChoices. Laura is an oncology clinical nurse specialist who has been providing integrative oncology clinical care, navigation, consultation, and education services for over 40 years. She is the co-creator and co-coordinator of the Integrative Oncology Navigation Training at Smith Center for Healing and the Arts in Washington, DC. Laura also manages the “Media Watch Cancer News That You Can Use” listserv for Smith Center/Commonweal. In her role as a palliative care educator and consultant, Laura has served as statewide Respecting Choices Faculty for the Virginia POST (Physician Orders for Scope of Treatment) Collaborative as well as provided statewide professional education on palliative and end-of-life care for the Virginia Association for Hospices and Palliative Care.

For CancerChoices, Laura curates content and research, networks with clinical and organizational partners, brings awareness and education of integrative oncology at professional and patient conferences and programs, and translates research into information relevant to the patient experience as well as clinical practice.

Laura sees her work with CancerChoices as a perfect alignment of all her passions, knowledge and skills in integrative oncology care. She is honored to serve you.

Laura Pole, RN, MSN, OCNS Senior Clinical Consultant

Nancy Hepp, MS

Lead Researcher and Program Manager
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Ms. Hepp is a researcher and communicator who has been writing and editing educational content on varied health topics for more than 20 years. She serves as lead researcher, program manager, and writer for CancerChoices. Her graduate work in research and cognitive psychology, her master’s degree in instructional design, and her certificate in web design have all guided her in writing and presenting information for a wide variety of audiences and uses. Nancy’s service as faculty development coordinator in the Department of Family Medicine at Wright State University also provided experience in medical research, plus insights into medical education and medical care from the professional’s perspective.

Nancy Hepp, MS Lead Researcher and Program Manager

Last update: June 29, 2023

Last full literature review: November 2021

CancerChoices provides information about integrative in cancer care, a patient-centered approach combining the best of conventional care, self care and evidence-informed complementary care in an integrated plan cancer care. We review complementaryin cancer care, complementary care involves the use of therapies intended to enhance or add to standard conventional treatments; examples include supplements, mind-body approaches such as yoga or psychosocial therapy, and acupuncture therapies and self-care lifestyle actions and behaviors that may impact cancer outcomes; examples include eating health-promoting foods, limiting alcohol, increasing physical activity, and managing stress practices to help patients and professionals explore and integrate the best combination of conventionalthe cancer care offered by conventionally trained physicians and most hospitals; examples are chemotherapy, surgery, and radiotherapy and complementary therapies and practices for each person.

Our staff have no financial conflicts of interest to declare. We receive no funds from any manufacturers or retailers gaining financial profit by promoting or discouraging therapies mentioned on this site.