Copper Chelation

• Preliminary evidencesignificant effects in small or poorly designed clinical studies OR conflicting results in adequate studies but a preponderance of evidence of an effect (this is the CancerChoices definition; other researchers and studies may define this differently) of a doubling of average time to disease progression among people with mesothelioma using TM following surgery
• Preliminary evidence of better progression-free survival compared to historical controls and markers of decreased microenvironment support for tumors among women with breast cancer, mostly triple-negative breast cancer, using TM
• Preliminary evidence of better overall survival among people with advanced esophageal cancer treated with TM and conventional therapies
• Weak evidenceone or more case studies, supported by animal evidence OR small treatment effects of limited clinical significance OR studies with no controls OR weak trends of effects (this is the CancerChoices definition; other researchers and studies may define this differently) of tumor response to copper chelation among people with advanced  colorectal, kidney cancer, or advanced cancer as a whole

See How can copper chelation help you? What the research says ›

What is your body terrain? ›

• Weak evidenceone or more case studies, supported by animal evidence OR small treatment effects of limited clinical significance OR studies with no controls OR weak trends of effects (this is the CancerChoices definition; other researchers and studies may define this differently) of reduced ceruloplasmin levels, fewer bone marrow-derived endothelial progenitor cells—critical for metastatic progression—and other components of the tumor microenvironment among people treated with agents to deplete copper

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We did not find any published studies investigating copper chelation for managing side effects.

• Preliminary evidencesignificant effects in small or poorly designed clinical studies OR conflicting results in adequate studies but a preponderance of evidence of an effect (this is the CancerChoices definition; other researchers and studies may define this differently) of a lower rate of relapse than expected among people with triple-negative breast cancer treated with TM
• Preliminary evidence of lower risk of recurrence than expected with TM in addition to chemo/radiotherapy followed by surgery

See How can copper chelation help you? What the research says ›

• Not mentioned in integrative cancer clinical practice guidelines
• Used in several of our program sources

See How do experts use copper chelation? ›

• Several known side effects, some of which could be dangerous; use requires careful monitoring by a health professional trained in this technique

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• Requires a prescription
• Very limited availability within the US
• Moderately expensive (more than $2000 US/year but less than $20,000 US)

See Affordability and access ›