Iodine - CancerChoices



As an essential nutrient, iodine is needed for thyroid function, and a deficiency is linked to higher risk of thyroid and stomach cancers. Some evidence shows that treatment with molecular iodine before breast cancer surgery may improve tumor response and reduce some side effects.

Iodine at a glance

Iodine is a mineral and essential nutrient found in foods including fish, seafood, kelp, dairy products, eggs, and iodized salt. Because iodine deficiency is a cause of underactive thyroid (hypothyroidism), corrective treatment with supplemental iodine may enable an underactive thyroid to resume making thyroid hormones that influence bone and brain development as well as other functions. A thyroid hormone deficiency or insufficiency may also contribute to cancer growth or other conditions.

Radioactive iodine is widely used as a conventional treatmentthe cancer care offered by conventionally trained physicians and most hospitals; examples are chemotherapy, surgery, and radiotherapy for many types of cancer and also overactive thyroid (hyperthyroidism). Additional experimental uses of radioactive iodine are being investigated. Information on these treatments is widely available from conventional treatment sources.

In this review, we assess the impact of iodine deficiency and use of dietary iodine or molecular iodine supplements in cancer care. To date, very little research has investigated this use of molecular iodine supplements. One small study found better survival and tumor response rates, plus fewer side effects of treatment, when molecular iodine was used in addition to surgery and chemotherapy for breast cancer. An iodine deficiency may increase the risk of thyroid cancer or stomach cancer. No evidence shows that iodine supplements as a stand-alone treatment will improve cancer outcomes.

CancerChoices ratings for iodine

We rate iodine on seven attributes, with 0 the lowest rating and 5 the highest. We rate the strength of the evidence supporting the use of iodine for a medical benefit, such as improving treatment outcomes or managing side effects.

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2

Improving treatment outcomes

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0

Optimizing your body terrain

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2

Managing side effects and promoting wellness

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3

Reducing cancer risk

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2

Use by integrative oncology experts

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3

Safety

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4

Affordability and access

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Keep reading about iodine

Authors

Nancy Hepp, MS

Lead Researcher
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Ms. Hepp is a researcher and communicator who has been writing and editing educational content on varied health topics for more than 20 years. She serves as lead researcher and writer for CancerChoices and also served as the first program manager. Her graduate work in research and cognitive psychology, her master’s degree in instructional design, and her certificate in web design have all guided her in writing and presenting information for a wide variety of audiences and uses. Nancy’s service as faculty development coordinator in the Department of Family Medicine at Wright State University also provided experience in medical research, plus insights into medical education and medical care from the professional’s perspective.

Nancy Hepp, MS Lead Researcher

Laura Pole, MSN, RN, OCNS

Senior Clinical Consultant
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Laura Pole is senior clinical consultant for CancerChoices. Laura is an oncology clinical nurse specialist who has been providing integrative oncology clinical care, navigation, consultation, and education services for over 40 years. She is the co-creator and co-coordinator of the Integrative Oncology Navigation Training at Smith Center for Healing and the Arts in Washington, DC. Laura also manages the “Media Watch Cancer News That You Can Use” listserv for Smith Center/Commonweal. In her role as a palliative care educator and consultant, Laura has served as statewide Respecting Choices Faculty for the Virginia POST (Physician Orders for Scope of Treatment) Collaborative as well as provided statewide professional education on palliative and end-of-life care for the Virginia Association for Hospices and Palliative Care.

For CancerChoices, Laura curates content and research, networks with clinical and organizational partners, brings awareness and education of integrative oncology at professional and patient conferences and programs, and translates research into information relevant to the patient experience as well as clinical practice.

Laura sees her work with CancerChoices as a perfect alignment of all her passions, knowledge and skills in integrative oncology care. She is honored to serve you.

Laura Pole, MSN, RN, OCNS Senior Clinical Consultant

Reviewer

Susan Yaguda, MSN, RN

Manager at Atrium Health’s Levine Cancer Institute and CancerChoices Clinical Consultant
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Susan Yaguda, MSN, RN, has been a nurse for nearly 40 years, working in a variety of healthcare settings. She currently works in Charlotte, North Carolina, at Atrium Health’s Levine Cancer Institute as the manager for Integrative Oncology and Cancer Survivorship. She works with a multidisciplinary team to deliver holistic, evidence-based support and education for patients and care partners at any point along the trajectory of cancer care. She completed the Integrative Oncology Scholars Program through the University of Michigan in 2020, is certified as an Integrative Health Coach through Duke Integrative Medicine and has a post-graduate certificate in Nursing Education from the University of North Carolina, Charlotte. Susan also was awarded the Planetree International Scholar’s Award in 2018 and was recognized by the Daisy Foundation for Nurse Leadership in 2021. Susan has a particular interest in empowering patients and care partners with knowledge to help drive informed decision making and educating nurses on the benefits of integrative care for patients and self-care. She has presented nationally and internationally on integrative oncology and nursing education.

She and her husband, Mark, have two adult children and a very spoiled foxhound. She enjoys hiking, knitting, cooking, and pickleball.

“As a frequent consumer of Beyond Conventional Cancer Therapies, and now CancerChoices, for both professional education and patient support, it is an honor to have the opportunity to engage with the dedicated team at CancerChoices to serve those impacted by this disease.”  

 

Susan Yaguda, MSN, RN Manager at Atrium Health’s Levine Cancer Institute and CancerChoices Clinical Consultant

Last update: May 7, 2024

Last full literature review: April 2023

We are grateful for research support from Adriana Gutierrez Galvis.

CancerChoices provides information about integrativein cancer care, a patient-centered approach combining the best of conventional care, self care, and evidence-informed complementary care in an integrated plan cancer care. We review complementaryin cancer care, complementary care involves the use of therapies intended to enhance or add to standard conventional treatments; examples include supplements, mind-body approaches such as yoga or psychosocialtherapy, and acupuncture therapies and self carelifestyle actions and behaviors that may impact cancer outcomes; examples include eating health-promoting foods, limiting alcohol, increasing physical activity, and managing stress practices to help patients and professionals explore and integrate the best combination of conventionalthe cancer care offered by conventionally trained physicians and most hospitals; examples are chemotherapy, surgery, and radiotherapy and complementary therapies and practices for each person.

Our staff have no financial conflicts of interest to declare. We receive no funds from any manufacturers or retailers gaining financial profit by promoting or discouraging therapies mentioned on this site.

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